Volume : 3, Issue : 4, April - 2014

A Comparative Study of Second Trimester MTP With Use of Vaginal Misoprostol and Extra Amniotic Instillation of Ethacridine Lactate With Pge2 (Dinoprostone).

Dr. Sameer Darawade, Dr. Ketaki Junnare, Dr. Swati Mali

Abstract :

In a randomised controlled study conducted at B.J. Medical College Pune, 100 patients undergoing second trimester medical termination of pregnancy (MTP)were included. Methodology: Group A received tablets misoprostol 200 mcg vaginally every 6 hourly till abortion. Group B patients underwent extraamniotic instillation of 150 cc of ethacridine lactate with tablet dinoprostone. Patients were observed for induction abortion interval, completeness of abortion and complications. Results: 100% success rate was observed in group A. Induction abortion interval was significantly less in group A. It was not affected by gestational age. In group B induction abortion interval goes on reducing as gestational age advances. Average dose of misoprostol required for complete abortion is 621.92 mcg. No major complications were noted in any group. Conclusion: Misoprostol should be drug of choice for second trimester MTP as it is highly effective with significantly less induction abortion interval