Volume : 4, Issue : 1, January - 2015

HOMOCYSTEINE-A NOVEL RISK FACTOR FOR ATHEROVASCULAR DISEASE

Dr. Zalak Malav Gadani

Abstract :

<p>Background: Presence of mild to moderate hyperhomocysteinemia is an independent risk factor for atherosclerosis< /> in the coronary, cereal, and peripheral vasculature, and for vascular disease. Several traditional risk factors are< /> associated with total Homocysteine.< /> Objectives: To evaluate S .Homocysteine level as a risk factor for atherovascular disease and to assess correlation between traditional risk factors< /> and S. Homocysteine level.< /> Methods: Patients with atherovascular disease admitted in medical wards were enrolled. Traditional risk factors along with S. Homocysteine level< /> were measured and studied.< /> Results: Incidence of Homocysteinemia is found in 84% of cases, among which 69%of patient have moderate rise and 31% of patient have< /> intermediate rise in Homocysteine level. Homocysteine concentrations were higher in men than in women and increased with age. Several< /> traditional risk factors are associated with total Homocysteine. Homocysteine has more than a multiplicative effect on traditional risk factors.< /> Conclusion: Homocysteine level should be measured routinely in every patient who is suspected of having atherosclerosis.</p>