Volume : 4, Issue : 2, February - 2015

Anti-MRSA studies on active extracts from Tridax procumbens L.

V. A. Kamble, A. H. Moon

Abstract :

<p>The study was intended for the therapeutic management of methicillin resistant Staphylococcus aureus by the use of medicinal plant Tridax procumbens. A total of 472 clinical isolates of Staphylococcus aureus were included for the study. Anti&ndash;MRSA screening was done for methicillin resistance based on Kirby&ndash;Bauer disk diffusion method using oxacillin (1&micro;g) and methicillin (5&micro;g) discs. Antibacterial activity of MRSA was assayed using 20 different extracts obtained from polar and non&ndash;polar solvents. The significant inhibition zone range of 17&ndash;23 mm was obtained from methanol root extracts. The antibiotic susceptibility testing of S. aureus isolates revealed high degree of resistance (94.82%) to penicillin and ampicillin, while 5.17% isolates were sensitive to both antibiotics. The study concludes that, the screening of anti&ndash;MRSA potential of medicinal plants would help to rediscover the new therapeutic plant drugs for the management of emerging strains of the common pathogen.</p>