Volume : 4, Issue : 4, April - 2015

High level of circulating platelet derived microvesicles in bone tumors

Judit Donath, Patricia Palfi, Bence Gyorgy, Gyula Poor, Miklos Szendroi, Agnes Kittel, Edit I Buzas, Andras Falus, Gyorgy Nagy

Abstract :

<p>&nbsp;CoII, NiII, CuII and MnII complexes of Mannich base, as ligand, was prepared by condensation of aqueous semicarbazide,&nbsp;</p> <div>morpholine and pyridine&ndash;3&ndash;carboxaldehyde. The structure of the newly synthesized Mannich base was investigated by&nbsp;</div> <div>UV&ndash;Vis, IR, 1</div> <div>H&ndash;NMR, 13C&ndash;NMR, molar conductance and magnetic susceptibility studies. The antimicrobial activities of the&nbsp;</div> <div>ligand and metals complexes have been screened in vitro against the organisms E.faecalis, Proteus mirabilis, Bacillus cereus, E.aerogens, ESBL&nbsp;</div> <div>E.coli, ESBL K.pneumoniae, by disc diffusion and well diffusion techniques. It is observed that the coordination of metal ions has pronounced&nbsp;</div> <div>effect on the microbial activities of the ligand. The metal complexes have higher antimicrobial effect than the free ligand.</div>

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Judit Donath, Patricia Palfi, Bence Gyorgy, Gyula Poor, Miklos Szendroi, Agnes Kittel, Edit I Buzas, Andras Falus, Gyorgy Nagy High level of circulating platelet derived microvesicles in bone tumors Global Journal For Research Analysis, Vol: 4, Issue:


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