Volume : 5, Issue : 6, June - 2016
Clinical evaluation of the breath test with mixed triglycerides in chronic pancreatitis
S. Siminkovitch, B. Vladimirov, M. Kovacheva Slavova
Abstract :
<p><p>&nbsp;The main objective of this study was to determine sensitivity and specificity of C13 labeled eath test with mixed triglycerides (&sup1;&sup3;C-MTG BT) in patients with chronic pancreatitis (CP), and to compare results to imaging CT/MRCP data and Fecal-elastase-1. Study encompassed 40CP patients (26 males); mean aged 53.29 &plusmn; 14.09. Patients were divided according to CT/MRCP Camidge classification. &sup1;&sup3;C-MTG BT3 was analyzed by a mass-spectrometry and FE-1 by ELISA (ScheBo&reg; Biotech). Results: 30% of the patients were positive for &sup1;&sup3;C-MTG BT. We found a difference between &sup1;&sup3;C-MTG BT mean values for CT/MRCP subgroups 1-4, p&lt;0.001. &sup1;&sup3;C-MTG BT sensitivity and specificity for severe diseasewere80% and 85%. Agreement between &sup1;&sup3;C-MTG BT and FE-1 was 78%. Conclusion: there was a relationship between &sup1;&sup3;C-MTG BT levels and severity of morphological imaging data and FE-1 results. The combination of both tests, FE-1 and &sup1;&sup3;C-MTG BT may contribute to better PEI detection.</p></p>
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Download PDF Journal DOI : 10.15373/2249555XCite This Article:
S. Siminkovitch, B. Vladimirov, M. Kovacheva-Slavova Clinical Evaluation of The Breath Test With Mixed Triglycerides in Chronic Pancreatitis Global Journal For Research Analysis, Vol.5, Issue : 6 JUNE 2016