Volume : 5, Issue : 6, June - 2016

Prevalence, Microbial Profile and Antimicrobial Sensitivity Pattern of Pathogens isolated from Paediatric Patients in a Tertiary Care Hospital in Eastern India

Dr. Rina Das, Dr. Bimal Kumar Mandal

Abstract :

<p>&lt;p&gt;&amp;nbsp;Background : A prospective study was conducted at a tertiary care centre in Kolkata, with the aim of finding the profile of the pediatric urinary tract infection, bacterial pathogens and their antibiotic sensitivity pattern. Materials &amp;amp; methods: Urine sample of 642 patients, below 14 years, suspected to have urinary tract infection (UTI) were tested, bacterial agents were identified by semi-quantitative urine culture and antibiotic sensitivity was performed according Clinical laboratory standard institute (CLSI) guideline. Results: Out of 642 samples, 138(21.5%) showed significant bacteriuria where female:male 1.16:1. Among isolates E. coli (34.78%) followed by Klebsiella (31.88%). These agents were most sensitive to Imipenem(79.17%) and Amikacin (79.17%). Out of gram positive bacteria Staphylococcus aureus (15.21%) were predominant and mostly sensitive to Vancomicin (100%) and Linezolide (95.23%). MRSA (28.57%) and MDR (17.39%) among total gram negative were identified in this study.Conclusions: As drug resistance among bacterial pathogens is an evolving process, regular surveillance and monitoring is necessary to provide physician&amp;rsquo;s knowledge on the updated and most effective empirical treatment of UTIs in children to reduce their morbidity and renal damage.&lt;/p&gt;</p>