Volume : 5, Issue : 10, October - 2016

Disseminated Trichosporon spp infection in preterm newborn: a case report at tertiary care hospital in North India

Priyadarshini, Dhirendra Kumar, Arghya Das

Abstract :

<p>&nbsp;To report the case of disseminated Trichosporon spp infection in a newborn infant in tertiary care hospital, discussing a few aspects concerning management and treatment. A new spectrum of pathogens associated with severe infections in neonatal ICU has arisen, afflicting mainly newborn preterm infants weighing less than 1,000 g at birth. Infection with Trichosporon asahii is rare and often fatal in this group of patients. A case of Trichosporon spp fatal infection in a newborn weighing 815 g at birth is reported. Literature search in the main databases returned only nine articles, reporting 14 cases of infection with this fungus in preterm newborns.The rate of invasive fungal infection is around 6% in this group of patients, Trichosporon infection being a likely occurrence. Mortality rate in these cases is extremely high, but early treatment with triazole antifungals improves prognosis significantly.</p>