Volume : 5, Issue : 12, December - 2016

A Comparative Study of collagen dressing versus Conventional Wound dressings in Non-Healing diabetic ulcer

Dr. Chandrashekar. S, Dr. Suraj. J

Abstract :

<p>&nbsp;<b><i><u><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,serif">Aim</span></u></i></b><i><span style="font-size:12.0pt;line-height:&#10;115%;font-family:&quot;Times New Roman&quot;,serif">: To assess the efficiency of collagen compared to conventional wound care in improving the healing process in non healing diabetic ulcers and prove that collagen can be used as relatively low cost,and a better alternate in management diabetic ulcers.</span></i></p> <p class="MsoNormal"><i><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,serif">&nbsp;<b><u>Material and methods</u></b>: This is a randomised comparative study where data from 100 patients with non healing diabetic ulcer collected. Of which 50 underwent collagen dressings, remaining 50 underwent conventional wound care. The results were compared after 14 days. The variables were compared based on rate of granulation tissue formation as percentage of ulcer area covered and duration of hospital stay. The categorical variable was compared by chi square test and continuous variable by student t-test. A p value &lt; 0.005 was considered significant. <o:p></o:p></span></i></p> <p class="MsoNormal"><b><i><u><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,serif">Results</span></u></i></b><i><span style="font-size:12.0pt;line-height:&#10;115%;font-family:&quot;Times New Roman&quot;,serif">: 50 patients who underwent topical collagen, after 14 days mean rate of granulation tissue formation was 84%. Mean graft take up was 86.32% and mean hospital stay was 40.50 days. Remaining 50 patients who underwent conventional wound care mean rate of granulation formation was 58.72%. The Mean graft take up was only 74.74% of total ulcer surface area, mean hospital stay was58.52 days. <o:p></o:p></span></i></p> <p class="MsoNormal"><b><i><u><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,serif">Conclusion</span></u></i></b><i><span style="font-size:12.0pt;line-height:&#10;115%;font-family:&quot;Times New Roman&quot;,serif">: To conclude, collagen helps in faster healing of the diabetic ulcer and better graft takeup and reduces hospital stay of these patients.&nbsp;<o:p></o:p></span></i></p>