Volume : 5, Issue : 12, December - 2016

Acute Transvere Myelitis Following Japanese Enchephalitis Viral Infection : A Rare Presentation Of The Infection

Dr. Neil B. Palkhiwala, Dr. Tanvi R. Seth, Dr. Ami P. Parikh, Dr. Harsh V. Khatri

Abstract :

<p>&nbsp;<span lang="EN-IN" style="text-align: justify; font-family: &quot;Times New Roman&quot;, serif;">Japanese encephalitis (JE) is an important cause of epidemic encephalitis in southeast Asian countries. A huge population living in the endemic regions makes this disease a global health concern. JE is caused by Japanese encephalitis virus (JEV), a mosquito-borne virus, Single stranded positive sense RNA virus belonging to the genus&nbsp;<i>Flavivirus</i>&nbsp;(family Flaviviridae). WHO estimated that approximately 67,900 JE cases typically occur annually in the 24 JE-endemic countries, for an incidence of 1.8 per 100?000 overall.&nbsp;In India, many outeaks of JE have been reported since 1955. [1] Apart from encephalitis, </span><span style="text-align: justify; font-size: 12pt; line-height: 115%; font-family: &quot;Times New Roman&quot;, serif; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;">immune-mediated manifestation as acute transverse myelitis (ATM) have been rarely previously reported in JE.</span><span style="text-align: justify; font-size: 10pt; line-height: 115%; font-family: &quot;Times New Roman&quot;, serif;"> </span><span lang="EN-IN" style="text-align: justify; font-family: &quot;Times New Roman&quot;, serif;">The case mentioned here is a male patient presented with acute-onset bilateral lower limb weakness followed by upper limb weakness without any signs of altered mentation.</span><span style="text-align: justify; font-size: 12pt; line-height: 115%; font-family: &quot;Times New Roman&quot;, serif; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;">&nbsp;</span><span lang="EN-IN" style="text-align: justify; font-family: &quot;Times New Roman&quot;, serif;">MRI cervico-dorsal Spine findings suggested Signal Intensity Alterations from the C2 to D10 levels. Corticosteroid pulse therapy for 5 days showed Improvements in power with complete recovery of other symptoms as well.</span></p> <p class="MsoNormal" style="text-align:justify"><span lang="EN-IN" style="font-family:&quot;Times New Roman&quot;,serif">&nbsp;< /> <o:p></o:p></span></p>