Volume : 5, Issue : 12, December - 2016

Effectiveness Of Prognostic Factors Influencing The Disease Free Survival In Non Metastatic Renal Cell Carcinoma.

Dr. Ram Reddy Ch, Dr. Rahul Devraj, Dr. Deepak Cheni, Dr. Sabarinath B, Dr. Vidyasagar S, Dr. Ramchandraiah G

Abstract :

<p>&nbsp;<b style="text-align: justify;">Aim:</b></p> <p class="Body" style="text-align:justify;line-height:200%"><o:p></o:p></p> <p class="Body" style="text-align:justify;line-height:200%">To analyze the clinical and pathological variables that are recognized as prognostic factors for RCC.<o:p></o:p></p> <p class="Body" style="text-align:justify;line-height:200%"><o:p>&nbsp;</o:p></p> <p class="Body" style="text-align:justify;line-height:200%"><b><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,serif">Materials and methods: <o:p></o:p></span></b></p> <p class="Body" style="text-align:justify;line-height:200%">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; This is a Retrospective study of patients who underwent radical nephrectomy during the period from Aug 2015 to Aug 2016 at Nizam&rsquo;s Institute of Medical sciences-Hyderabad. A Total of 52 patients who are effected with renal cell carcinoma were included excluding those patients who are effected with RCC under 18yrs, with metastatic RCC and bilateral RCC. There performance status was assessed by eastern cooperative oncology group performance preoperatively.<o:p></o:p></p> <p class="Body" style="text-align:justify;line-height:200%"><o:p>&nbsp;</o:p></p> <p class="Body" style="text-align:justify;line-height:200%"><b><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,serif">Results:<o:p></o:p></span></b></p> <p class="Body" style="text-align:justify;line-height:200%">Total 52 patients are included in the study, of these majority of the patients are between 40-60yrs of age(60.7%).46.1% of patients has ECOG performance score 0, SSIGN score is of 3-5 in 67.3%, 55.7% of patients are at intermediate risk according to UCLA risk group. One year disease free survival was noted in 82.6% of patients.<o:p></o:p></p> <p class="Body" style="text-align:justify;line-height:200%"><o:p>&nbsp;</o:p></p> <p class="Body" style="text-align:justify;line-height:200%"><b><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,serif">&nbsp;</span></b></p> <p class="Body" style="text-align:justify;line-height:200%"><b><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,serif">Conclusion:<o:p></o:p></span></b></p> <p class="Body" style="text-align:justify;line-height:200%">Available prognostic models like UISS and SSIGN score designs proved to be useful models for assessing prognosis of non metastatic RCC at one year of follow up.<o:p></o:p></p> <p class="Body" style="text-align:justify;line-height:200%"><b><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,serif">&nbsp;</span></b></p>