Volume : 5, Issue : 12, December - 2016

Comparison of the diagnostic accuracy of FNAC and BIOPSY in the diagnosis of a palpable breast lump

Padhy Biren, Khan Perwez Alam, Hansa Jagdish

Abstract :

<p>&nbsp;<b style="text-align: justify;"><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,sans-serif">OBJECTIVE: </span></b><span lang="EN-IN" style="text-align: justify; font-size: 12pt; line-height: 115%; font-family: Arial, sans-serif;">To study and compare the results of FNAC of east lumps preoperatively with that of the post operative histopathological examination and analyse the accuracy of FNAC in their diagnosis</span></p> <p class="MsoNormal" style="margin-left:.5in;text-align:justify;text-justify:&#10;inter-ideograph"><b><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,sans-serif">DESIGN:</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,sans-serif"> The study conducted was prospective (Canadian Task Force Classification II-I)<o:p></o:p></span></p> <p class="MsoNormal" style="margin-left:.5in;text-align:justify;text-justify:&#10;inter-ideograph"><b><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,sans-serif">PATIENTS:</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,sans-serif"> The present study included 200 patients who presented with east lumps and admitted to the surgery department of IMS Medical College &amp; SUM Hospital, Bhubaneswar and who underwent FNAC and subsequent east lump excision as per their nature. The period of study was from October 2014 to September 2016 over a 2 year period.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-left:.5in;text-align:justify;text-justify:&#10;inter-ideograph"><b><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,sans-serif">MEASUREMENTS AND MAIN RESULTS:</span></b><span lang="EN-IN" style="font-size:12.0pt;&#10;line-height:115%;font-family:&quot;Arial&quot;,sans-serif">&nbsp;&nbsp; Patient average age was 40.5 yrs. The female to male ratio was 32.3: 1 with a female preponderence.The majority of the lumps were benign and premenopausal. FNAC gave 71% lumps to be benign and 29% as malignant. Histopathology confirmed 65.5% to be benign 2.5% to be inflammatory and 32% to be malignant. The sensitivity and specificity in detecting malignancy was 90.6% and 100% respectively. The overall accuracy of FNAC was 97%.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-left:.5in;text-align:justify;text-justify:&#10;inter-ideograph"><b><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,sans-serif">CONCLUSION:</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Arial&quot;,sans-serif"> In our experience of 200 patients who underwent FNAC and subsequent excision for their east lumps and histopathological confirmation, it was found that FNAC, though not confirmatory is a reliable screening method for diagnosis of east lumps and correlates well with histopathology. The findings in our series were more or less similar to those deduced in other series.<o:p></o:p></span></p>