Volume : 6, Issue : 1, January - 2017

A study of prevalence of left ventricular diastolic dysfunction and its correlation with left ventricular hypertrophy in patients with newly diagnosed hypertension by Doppler echocardiography

Dr. Sunita Gupta, Dr Neha Mishra, Dr. Vijay, Dr. Jasmeen Chahal

Abstract :

<p>&nbsp;<b style="text-align: justify;"><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,serif">Introduction</span></b><span lang="EN-IN" style="text-align: justify; font-size: 12pt; line-height: 115%; font-family: &quot;Times New Roman&quot;, serif;">:</span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify"><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&#10;&quot;Times New Roman&quot;,serif">&nbsp;Hypertension leads to structural and functional adaptation leading to left ventricular hypertrophy and impaired diastolic function are common effects on heart. Doppler echocardiography is an important and non invasive method of evaluating hypertensive patients for diastolic dysfunction. Aim of study was to find out the prevalence of left ventricular diastolic dysfunction in newly diagnosed hypertensive patients and to find correlation of left ventricular hypertrophy with diastolic dysfunction. <b>Materials and methods</b>: <o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify"><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&#10;&quot;Times New Roman&quot;,serif">The study was conducted at M.M. Institute of Medical Sciences and Research, Mullana, Ambala India. Fifty newly diagnosed asymptomatic hypertensive with age &lt;55 years were taken from OPD and indoor wards of medicine department. According to JNC-8 criteria stage 1 and stage 2 were considered for this study. Blood pressure monitoring was done in all selected patients by using sphygmomanometer. Two readings were taken at the same visit in sitting position after a gap of 10-15 minutes. ECG (electrocardiogram) was done to exclude any major coronary artery disease. 2-D Echocardiography was done in all selected patients using M mode, two-dimensional and Doppler. <b>Observations-</b><o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify"><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&#10;&quot;Times New Roman&quot;,serif">58% (29) patients had left ventricular hypertrophy (LVH). 42%(21) patients had no left ventricular hypertrophy (LVH). In our study the prevalence of diastolic dysfunction in newly diagnosed hypertensive patient was 86%.&nbsp; The commonest type of diastolic dysfunction was impaired relaxation 86%, pseudonormal pattern in 10.34% and restrictive pattern of LV diastolic dysfunction in 3.4% of hypertensives with LVH. <o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify"><b><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,serif">Conclusion:</span></b><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,serif"><o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify"><span lang="EN-IN" style="font-size:12.0pt;line-height:115%;font-family:&#10;&quot;Times New Roman&quot;,serif">&nbsp;The conclusion of present study is stronger association of blood pressure with LVH, very high prevalence of diastolic dysfunction in hypertensive population and significant correlation of diastolic dysfunction with LVH.<o:p></o:p></span></p>

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Cite This Article:

Dr. Sunita Gupta, Dr Neha Mishra, Dr. Vijay, Dr. Manik Aggarwal, Dr. Jasmeen Chahal, A study of prevalence of left ventricular diastolic dysfunction and its correlation with left ventricular hypertrophy in patients with newly diagnosed hypertension by Doppler echocardiography, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-6, Issue-1, January‾2017


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