Volume : 6, Issue : 1, January - 2017

Zinc Sulphate Induced Micronucleus Test and Mitotic Index on Channa punctatus in vivo

Pradipta Kumar Sarangi

Abstract :

<p>&nbsp;<span style="text-align: justify; font-size: 12pt; line-height: 200%;">Zinc plays an essential role in wide range of cellular process,including defence against free redicals and mantaining genomic stability of aquatic fauna. In the present study, we analysed the induced mitotic index of dividing cells of kidney and micronuclei in peripheral erythrocytes of <i>Channa punctatus</i> following in vivo exposure of three different concentrations&nbsp; ZnSO4.7H2O. Our result revealed that Zinc&nbsp; induced significantly high incidences of micronuclei in peripheral erythrocytes, and inhibited mitotic index and caused considerable delay in the generation time of kidney cells in treated organisms. .Time and concentration related response of the chemical as observed in this study clearly indicated the genotoxic nature of&nbsp; Zinc Sulphate </span><span style="text-align: justify; font-size: 12pt; line-height: 200%;">significantly i.e. (p&le;0.05 to p&le;0.01) .&nbsp;</span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%"><span style="font-size:12.0pt;mso-bidi-font-size:&#10;11.0pt;line-height:200%"><o:p></o:p></span></p>