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MENUVolume : 6, Issue : 3, March - 2017
Low-Grade Fibromyxoid SarcomaA Case Report and Review of Literature
M . K. Paswan, M . A. Ansari, A. K. Shrivastav
Abstract :
<p> <span style="text-align: justify;"> </span><span style="text-align: justify;">Low-grade</span><span style="text-align: justify;"> </span><span style="text-align: justify;">fiomyxoid </span><span style="text-align: justify;"> </span><span style="text-align: justify;">sarcoma </span><span style="text-align: justify;"> </span><span style="text-align: justify;">(LGFMS) </span><span style="text-align: justify;"> </span><span style="text-align: justify;">is </span><span style="text-align: justify;"> </span><span style="text-align: justify;">a rare </span><span style="text-align: justify;"> </span><span style="text-align: justify;">neoplasm </span><span style="text-align: justify;"> </span><span style="text-align: justify;">with </span><span style="text-align: justify;"> </span><span style="text-align: justify;">a </span><span style="text-align: justify;"> </span><span style="text-align: justify;">tendency</span></p> <p style="text-align:justify;line-height:115%"><o:p></o:p></p> <p style="text-align:justify;line-height:115%"> to develop in deep soft tissue of young adults.<sup> </sup><sup><span style="font-family:"Calii",sans-serif;mso-bidi-font-family: "Times New Roman"">(1)</span></sup> It is also referred to as “Evans <o:p></o:p></p> <p style="text-align:justify;line-height:115%">tumor”, “<span style="mso-bidi-font-size: 24.0pt;line-height:115%">Hyalinizing spindle cell tumor with giant rosettes” and “Low-grade <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">fiosarcoma with palisaded granuloma like bodies”.<sup>(2,3) </sup> LGFMS is considered a <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">diagnostic dilemma </span> <span style="mso-bidi-font-size: 24.0pt;line-height:115%">because of its innocuous and varied histological features that <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">can be potentially confused </span> <span style="mso-bidi-font-size:24.0pt; line-height:115%">with other benign or low-grade fiomyxoid lesions. <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">This report is aimed at reinforcing </span> <span style="mso-bidi-font-size:24.0pt; line-height:115%">the need to recognize LGFMS as a sarcoma <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">despite its deceptively benign histological </span> <span style="mso-bidi-font-size: 24.0pt;line-height:115%">appearance. <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><b>Case Report:</b><span style="mso-bidi-font-size:24.0pt;line-height:115%"><o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">A 20-year-old female patient presented to the surgery Out Patient Department <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">with a painless, deeply situated mass in the proximal extremity (right forearm), <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">present for 5 years. Patient was referred to the pathology department for <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">Fine Needle Aspiration Cytology (FNAC). FNAC was suggestive of a benign <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">mesenchymal lesion of neural or fioblastic origin. This was followed by excision. <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">Pathological examination of the excised swelling revealed a grossly circumscribed, <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">Unencapsulated tumor measuring 8 x5 x3 cms in size. The cut surface varied from <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">being gray white, firm and fious to gelatinous or myxoid. Microscopy revealed <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">cellular areas constituted by bland spindle shaped fioblasts, alternating with less <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">cellular myxoid areas. A typical pattern of intermixed, sweeping bands of fious and <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">myxoid tissue, focal areas of storiform architecture and concentric perivascular <o:p></o:p></span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%"> </span></p> <p style="text-align:justify;line-height:115%"><span style="mso-bidi-font-size: 24.0pt;line-height:115%">cuffs of slender spindle cells was seen ( Figure 1 ). </span><span style="mso-bidi-font-size:24.0pt;line-height:115%;mso-fareast-language:EN-US; mso-no-proof:yes"><o:p></o:p></span></p>
Keywords :
Cite This Article:
M .K. paswan, M .A. Ansari, A. K. shrivastav, Low-Grade Fibromyxoid Sarcoma–A Case Report and Review of Literature, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-6, Issue-3, March‾2017
