Volume : 6, Issue : 3, March - 2017
EVALUATION OF ANTIOXIDANT PROPERTY OF EMPAGLIFLOZIN– DPPH ASSAY AND NITRIC OXIDE SCAVENGING ACTIVITY (IN-VITRO METHOD)
Dr. M. Sindhuja, Dr N. S Muthiah, Dr. R. Rajeswari
Abstract :
<p> <b><span style="font-size:12.0pt; line-height:150%;font-family:"Times New Roman",serif"> Background:</span></b><span style="font-size: 12pt; line-height: 150%; font-family: "Times New Roman", serif;"> Diabetes Mellitus is a group of metabolic disease with increasing prevalence recently. Although obesity and physical inactivity accounts for the major risk for type II Diabetes Mellitus, increased production of free radicals leading to oxidative stress may also contribute to the pathogenesis of type II Diabetes Mellitus. Hence it is important to discover a hypoglycemic drug that reduces oxidative stress in diabetic patients.</span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height: 150%"><b><span style="font-size:12.0pt; line-height:150%;font-family:"Times New Roman",serif"> Aim and Objective:</span></b><span style="font-size:12.0pt;line-height:150%;font-family:"Times New Roman",serif"> This study, was performed to evaluate the antioxidant efficacy of Empagliflozin with Ascorbic acid by DPPH assay and nitric oxide scavenging activity, an in –vitro method. <o:p></o:p></span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height: 150%"><b><span style="font-size:12.0pt; line-height:150%;font-family:"Times New Roman",serif"> Results:</span></b><span style="font-size: 12.0pt;line-height:150%;font-family:"Times New Roman",serif"> This study show that Empagliflozin on comparison with Ascorbic acid has antioxidant property and can be effectively used for reducing oxidative stress in patients with Diabetes<o:p></o:p></span></p>
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Download PDF Journal DOI : 10.15373/2249555XCite This Article:
Dr. M.Sindhuja, Dr N.S Muthiah, Dr. R. Rajeswari, EVALUATION OF ANTIOXIDANT PROPERTY OF EMPAGLIFLOZIN– DPPH ASSAY AND NITRIC OXIDE SCAVENGING ACTIVITY (IN-VITRO METHOD), GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-6, Issue-3, March‾2017