Volume : 6, Issue : 3, March - 2017

Prevalence of dermatoses among naxal infested tribal villagers: A community based study from South Chhattisgarh, India

Dr. Yasha Upendra, Dr. Naveen Keswani, Dr. Sampreeti Sendur, Dr. Abhishek Pallava

Abstract :

<p>&nbsp;<b><i><span style="font-size:12.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,serif">Background: </span></i></b><i><span style="font-size:12.0pt;line-height:115%;font-family:&#10;&quot;Times New Roman&quot;,serif">Hypertension is one among the leading disease causing morbidity and mortality irrespective of other co morbid conditions. Hypothetically the culprit<b> </b>behind has been the<b> </b>accumulation of free radicals causing oxidative stress. Oxidative stress plays a vital role in pathophysiological changes in hypertension. Prescribing 2 or 3 medications &nbsp;is one among the cause for major drug interaction and hence to prevent it, necessity of the pertained drug for the disease to act as a scavenger is the need of the hour in current scenario. <b>Objective:</b> In this study we are intended to find antihypertensive drug Carvedilol (3.125mg) percentage of scavenging action of nitric oxide<b> </b>radicals against the standard ascorbic acid and commercially available vitamin C.<b> Result:</b> It is found that the nitric oxide scavenging activity of Carvedilol (3.125) is quite appreciable (75.74%) when compared to ascorbic acid (98.5%) and Vit C(90.58%).</span></i></p> <p class="MsoNormal"><i><span style="font-size:12.0pt;line-height:115%;font-family:&#10;&quot;Times New Roman&quot;,serif"><o:p></o:p></span></i></p>