Volume : 6, Issue : 4, April - 2017

Comparative study of Preoperative Sedation and Face Masks Acceptance of Intranasal Dexmedetomidine versus Intranasal Midazolam of age group 2-7 years

Chandra Rajesh, Prakash Shanti, Sinha Ritesh Kumar, Kumar Harish, Singh Sumit Kumar

Abstract :

<p>&nbsp;<span style="text-align: justify; font-size: 12pt; line-height: 150%; font-family: &quot;Times New Roman&quot;, serif;">Background : Face mask acceptance is very important in childrens. Due to anxiety and fear there is increase in heart rate, blood pressure and behavioral changes. The purpose of this study is to compare sedation and face mask acceptance in age goup 2-7 years between dexmedotomidine and midazolam group.</span><span style="text-align: justify; font-size: 12pt; line-height: 150%; font-family: &quot;Times New Roman&quot;, serif; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;"> Methods: This study was conducted as a randomized clinical trial among 60 childrens undergone elective surgery. The patients were randomly allocated into two groups. </span><span style="text-align: justify; font-size: 12pt; line-height: 150%; font-family: &quot;Times New Roman&quot;, serif;">&nbsp;Group<b> D</b> - children received dexmedetomidine, 1 &micro;g/kg intranasally 40 &ndash; 45 min prior to anaesthesia induction.Group <b>M</b> - children received midazolam 0.2 mg/kg intranasally 40 &ndash; 45 min prior to anesthesia induction.<span style="background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;"> Results </span></span><span style="text-align: justify; font-size: 12pt; line-height: 150%; font-family: &quot;Times New Roman&quot;, serif;">10% of children in Dexmedetomidine group and 30% of the children in Midazolam group were sleepy and drowsy, eyes open, 36.7% of children in Dexmedetomidine group and 10% in Midazolam group had their eyes closed but verbally arousable, 33.3% of dexmedetomidine and 40% of the Midazolam group had their eyes closed but arousable with light physical stimulation and 20% in both the groups had eyes closed but not arousable with physical stimulation</span><span style="text-align: justify; font-size: 12pt; line-height: 150%; font-family: &quot;Times New Roman&quot;, serif; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;"> .Conclusion: </span><span style="text-align: justify; font-size: 12pt; line-height: 150%; font-family: &quot;Times New Roman&quot;, serif;">Dexmedetomidine and midazolam had shown the same effectiveness in Parental separation. pre induction&nbsp; mask acceptance. Dexmedetomidine and midazolam had shown the same effectiveness in&nbsp; pre induction&nbsp; mask acceptance.</span></p> <p class="MsoNormal" style="text-align:justify;line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:&quot;Times New Roman&quot;,serif"><o:p></o:p></span></p>