Volume : 6, Issue : 5, May - 2017

Upper GI EndoscopicManifestations in Bronchial Asthma

Dr. Caroline Selvi, K, Dr. Kandasamy Alias Kumar. E

Abstract :

<p>&nbsp;<b><span lang="EN-IN" style="font-size:7.0pt;mso-bidi-font-size:&#10;10.0pt;line-height:115%;font-family:&quot;Thorndale AMT&quot;,serif;mso-fareast-font-family:&#10;Calii;mso-fareast-theme-font:minor-latin;mso-bidi-font-family:&quot;Thorndale AMT&quot;;&#10;mso-ansi-language:EN-IN;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">AIM </span><span lang="EN-IN" style="font-size:10.0pt;line-height:115%;font-family:&#10;&quot;Thorndale AMT&quot;,serif;mso-fareast-font-family:Calii;mso-fareast-theme-font:&#10;minor-latin;mso-bidi-font-family:&quot;Thorndale AMT&quot;;mso-ansi-language:EN-IN;&#10;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">:1.</span></b><span lang="EN-IN" style="font-size:10.0pt;line-height:115%;font-family:&quot;Thorndale AMT&quot;,serif;&#10;mso-fareast-font-family:Calii;mso-fareast-theme-font:minor-latin;mso-bidi-font-family:&#10;&quot;Thorndale AMT&quot;;mso-ansi-language:EN-IN;mso-fareast-language:EN-US;mso-bidi-language:&#10;AR-SA">To document the various upper gastro-intestinal endoscopic as well as histologic findings of lower esophagus in patients with onchial asthma.2. To correlate the association with duration and severity of onchial asthma.3.To document the presence of NERD (Negative Endoscopic Reflux Disease) in patients with&nbsp;&nbsp;&nbsp; onchial asthma. 4.Endoscopic / histological correlation of esophagus status in patients with onchial asthma.</span><b><span lang="EN-IN" style="font-size:8.0pt;mso-bidi-font-size:10.0pt;line-height:115%;&#10;font-family:&quot;Thorndale AMT&quot;,serif;mso-fareast-font-family:Calii;mso-fareast-theme-font:&#10;minor-latin;mso-bidi-font-family:&quot;Thorndale AMT&quot;;mso-ansi-language:EN-IN;&#10;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">MATERIALS AND METHODS</span><span lang="EN-IN" style="font-size:10.0pt;line-height:115%;font-family:&quot;Thorndale AMT&quot;,serif;&#10;mso-fareast-font-family:Calii;mso-fareast-theme-font:minor-latin;mso-bidi-font-family:&#10;&quot;Thorndale AMT&quot;;mso-ansi-language:EN-IN;mso-fareast-language:EN-US;mso-bidi-language:&#10;AR-SA">:</span></b><span style="font-size:10.0pt;line-height:115%;font-family:&#10;&quot;Times New Roman&quot;,serif;mso-fareast-font-family:&quot;Times New Roman&quot;;mso-ansi-language:&#10;EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">.</span><b><span lang="EN-IN" style="font-size:10.0pt;line-height:115%;font-family:&quot;Thorndale AMT&quot;,serif;&#10;mso-fareast-font-family:Calii;mso-fareast-theme-font:minor-latin;mso-bidi-font-family:&#10;&quot;Thorndale AMT&quot;;mso-ansi-language:EN-IN;mso-fareast-language:EN-US;mso-bidi-language:&#10;AR-SA"> Inclusion Criteria :</span></b><span lang="EN-IN" style="font-size:10.0pt;&#10;line-height:115%;font-family:&quot;Thorndale AMT&quot;,serif;mso-fareast-font-family:&#10;Calii;mso-fareast-theme-font:minor-latin;mso-bidi-font-family:&quot;Thorndale AMT&quot;;&#10;mso-ansi-language:EN-IN;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">Thirty patients who were diagnosed to have onchial asthma and having regular follow up in thoracic medicine out patient clinic were included in the study.. <b>Exclusion Criteria </b>patients with systematicIllnesses &nbsp;Hypertension, Diabetes Mellitus, Chronic renal failure, Rheumatological diseases. and patients with habits of smoking alcoholism, tobacco ingestion, NSAID intake.Patients at extremes of age.(&lt;13 &amp;&gt;60)Pregnancy, acute exacerbation of symptoms. Routine investigations were taken along with Pulmonary Function Tests. Upper gastro-intestinal endoscopy was done with three biopsy samples were taken for each patient from the gastro oesophageal junction . Histological assessment of the samples were done.<b>Results</b>: Various parameters were tabulated and analysed.</span><span lang="EN-IN" style="font-size:10.0pt;line-height:115%;font-family:&quot;Times New Roman&quot;,serif;&#10;mso-fareast-font-family:Calii;mso-fareast-theme-font:minor-latin;mso-ansi-language:&#10;EN-IN;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">Out of the 30 paitents. 15 were male (50%) and 15 were female (50%). Of the 30 patients studied 17 had abnormal endoscopy findings thus comprising of 56.67% . Out of the 15 males studied 10 had abnormal findings (66.67%) and out of the 15 female, 7 had abnormal finding (46.67%).. Reflux esophagitis was found in 12 patients (40%) and pulled up gastro-oesophageal junction consistent with hiatus hernia was found in 2 patients (6.67%).<b>Conclusions:</b> Prevalence of Reflux esophagitis is more common in asthmatics reconfirmed in this study. Reflux esophagitis is&nbsp; proportional to the duration and severity of onchial asthma. This study established the Importance of histopathology in negative endoscopic reflux</span></p>