Volume : 6, Issue : 5, May - 2017

Clinical Assessment of the effects of Prostaglandin E1 on Orthodontic Tooth Movement in Maxillary Arch: An In vivo Split Mouth Study

Dr. Swati Jain, Dr. Nishitha C. Gowda, Dr. Vennila N. Swamy, Dr. Santosh Ramegowda

Abstract :

<p>&nbsp;<span style="font-family: &quot;Times New Roman&quot;, serif;">Clinical Assessment of the effects of Prostaglandin E1 on Orthodontic Tooth Movement in Maxillary Arch: An In vivo Split Mouth Study</span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%"><span lang="EN-GB" style="font-family: &quot;Times New Roman&quot;, serif;">Introduction:</span><span lang="EN-GB" style="font-family:&quot;Times New Roman&quot;,serif"> Prostaglandins are one of the chemical mediators influencing the orthodontic tooth movement. (OTM)<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;line-height:200%"><span lang="EN-GB" style="font-family:&quot;Times New Roman&quot;,serif">Aim: To study the effect of exogenous application of Prostaglandin E1 (PgE1) gel on OTM in routine patients.<o:p></o:p></span></p> <p class="MsoNormal" style="line-height:200%"><span lang="EN-GB" style="font-family:&#10;&quot;Times New Roman&quot;,serif">Methodology: Fifteen patients were selected who required extraction of first premolars for the correction of malocclusion. After routine banding, bonding, initial alignment, en-mass retraction using appropriate appliances, they were treated with topical application of 3 microgram of PGE1 gel on test side and placebo gel on control side in four sessions. The OTM was measured clinically on patients and models.<o:p></o:p></span></p> <p class="MsoNormal" style="line-height:200%"><span lang="EN-GB" style="font-family:&#10;&quot;Times New Roman&quot;,serif">Results: There was statistically significant increase in OTM on test side as compared with control side.<o:p></o:p></span></p> <p class="MsoNormal" style="line-height:200%"><span lang="EN-GB" style="font-family:&#10;&quot;Times New Roman&quot;,serif">Conclusion: PGE1gel is an effective method for faster OTM.<o:p></o:p></span></p>