Volume : 6, Issue : 5, May - 2017

Effectiveness of using "Physiological ICSI" in patients with severe male factor infertility: A randomized controlled trial

Dr. Preetha. P. R, Prof. Dr. Aleyamma. T. K, Dr. Mohan S Kammath, Dr. K. Muthukumar

Abstract :

<p>&nbsp;<span style="text-align: justify; font-size: 12pt; line-height: 150%; font-family: &quot;Times New Roman&quot;, serif;">A randomised controlled trial was conducted to</span><b style="text-align: justify;"><span style="font-size: 14pt; line-height: 150%; font-family: &quot;Times New Roman&quot;, serif;"> </span></b><span style="text-align: justify; font-size: 12pt; line-height: 150%; font-family: &quot;Times New Roman&quot;, serif;">investigate whether the patients with severe male factor infertility will benefit by &ldquo;Physiological ICSI&rdquo;. Written informed consent was obtained from each subject once they agreed for the study. Randomization was done with sealed envelopes [Conventional ICSI (ICSI) and &ldquo;Physiological ICSI&rdquo; (PICSI)] on the day of oocyte retrieval after examining the semen sample of the husband. The pregnancy rate among the two different groups did not vary. There was only one biochemical pregnancy which belonged to the ICSI group. So the clinical pregnancy rate was higher than in the PICSI group, the difference of which is not statistically significant. Even though the cumulative pregnancy rate was 58 % in PICSI group and 33 % in ICSI group, the difference was not statistically significant.</span></p> <p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;text-align:&#10;justify;text-justify:inter-ideograph;line-height:150%;mso-layout-grid-align:&#10;none;text-autospace:none"><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Times New Roman&quot;, serif;"><b><o:p></o:p></b></span></p>