Volume : 6, Issue : 4, April - 2017

SEROPREVALENCE OF TOXOPLASMA AND RUBELLA INFECTIONS IN BAD OBSTETRIC HISTORY PATIENTS AT A TERTIARY CARE HOSPITAL

Anita E. Chand, Namita Garg, Sarita Rawat

Abstract :

<p>&nbsp;Introduction: Toxoplasma gondii&nbsp;&nbsp; and Rubella virus&nbsp; infections are one of&nbsp; the contributing causes of Bad Obstetric History .&nbsp;&nbsp; These infections in pregnancy results in &nbsp;various congenital malformations,&nbsp; adverse outcome of&nbsp;&nbsp; foetus &amp; pregnancy. Objective:To evaluate the seroprevalence of Toxoplasma gondii and Rubella virus infections in women with Bad Obstetric History patients.&nbsp;&nbsp; Materials &amp; Methods :.Determination of Toxoplasma&nbsp; and Rubella IgM &amp;IgG antibodies was done in the serum samples collected from BOH patients using ELFA (Enzyme Linked Flourescent Assay ) technique on mini VIDAS. Results: Out of total 100 BOH patients included in the study, seroprevalence of Toxo IgM was 2%,Toxo IgG&nbsp; was 6%, Rubella IgM was 2% and Rubella IgG was 84%.&nbsp;&nbsp; Conclusion:In order to&nbsp; prevent adverse effects of Toxoplasma&nbsp; and Rubella infections on pregnancy and foetus, routine screening&nbsp; for these infections in antenatal&nbsp; cases with&nbsp; bad&nbsp; obstetric history should be carried out for early diagnosis &amp; appropriate management.&nbsp;&nbsp;</p>