Volume : 6, Issue : 6, June - 2017
MISUSE OF ANTIBIOTICS IN DIARRHOEAL DISEASES
Dr. Anjali Edbor, Dr. Himanshu Dua, Dr. Parth Dalal
Abstract :
<p> <span style="font-family: "Times New Roman", serif; font-size: 12pt; text-align: justify;">Acute diarrhea remains one of the most important health issues worldwide. It is the commonest infectious disease in developing countries, mostly affecting children younger than five years old. Most cases are caused by virus and tend to present in a mild and self-limiting fashion, with the optimal treatment consisting solely of oral rehydration and nutritional support. Inappropriate use of antimicrobials is associated with allergic reactions, toxicity, super infection, and development of antimicrobial resistance. The excessive and inappropriate use of antibiotics adds an unnecessary economic burden to health care system and coincides with increase in drug resistant organisms. This study was undertaken with the aim to determine the percentage of children not needing antibiotics for acute diarrheal disease. Total 150 children between age group of 6 months-5 years admitted for age were taken into study and started on ORS + zinc therapy and stool culture with stool routine and microscopy was sent. Only patients presenting with blood and mucus or culture positive were started on antibiotics. Patients with dehydration were managed as per WHO guidelines. None had mortality. Study was conducted from June to September 2016. Data was analysedusing</span><span style="font-family: "Times New Roman", serif; font-size: 12pt; text-align: justify;"> </span><span style="font-family: "Times New Roman", serif; font-size: 12pt; text-align: justify;">McNamara chi square</span><span style="font-family: "Times New Roman", serif; font-size: 12pt; text-align: justify;"> </span><span style="font-family: "Times New Roman", serif; font-size: 12pt; text-align: justify;">test.</span><span style="font-family: "Times New Roman", serif; font-size: 12pt; text-align: justify;"> Results</span><b style="font-family: "Times New Roman", serif; font-size: 12pt; text-align: justify;">:</b><span style="font-family: "Times New Roman", serif; font-size: 12pt; text-align: justify;"> </span><span style="font-family: "Times New Roman", serif; font-size: 12pt; text-align: justify;">Out of 150 patients only 10 patients that is 6.6% had history of signs of bacterial infection. Only 4 out of 150 that is 2.6% had culture positive. The result was statistically significant with a P value < 0.023, Sensitivity: 40%, Specificity: 100%, PPV: 100%, NPV: 95.89%</span></p> <p class="MsoNormal" style="text-align:justify"><span style="font-size:12.0pt; line-height:115%;font-family:"Times New Roman",serif"><o:p></o:p></span></p>
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Download PDF Journal DOI : 10.15373/2249555XCite This Article:
Dr. Anjali Edbor, Dr. Himanshu Dua, Dr. Parth Dalal, MISUSE OF ANTIBIOTICS IN DIARRHOEAL DISEASES, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : VOLUME-6 | ISSUE‾6 | JUNE-2017