Volume : 6, Issue : 6, June - 2017
Characteristics of lower esophageal sphincter function and esophageal motility noted on High Resolution Esophageal Manometry in patients with reflux disease
Mayank Jain, Rajiv Baijal
Abstract :
<p> <span style="font-size: 14pt; text-align: justify;"> </span><span lang="EN-IN" style="font-size: 14pt; text-align: justify;">Aim- To study the characteristics of esophageal motility and LES function in patients with RE and NERD using high resolution esophageal manometry.</span></p> <p class="MsoNormal" style="margin-left:.25in;text-align:justify;text-justify: inter-ideograph;line-height:200%"><span lang="EN-IN" style="font-size:14.0pt; line-height:200%">Materials and methods- Twin Centre study which recruited all patients who underwent esophageal manometry for reflux symptoms from April 2014 to June 2016. They were divided into two groups -RE and NERD. Age and sex distribution and manometry parameters were analysed in the two groups.<o:p></o:p></span></p> <p class="MsoNormal" style="margin-left:.25in;text-align:justify;text-justify: inter-ideograph;line-height:200%"><span lang="EN-IN" style="font-size:14.0pt; line-height:200%">Results-A total of 98 patients (70 males, mean age 44 years) formed the study group.Thirty two patients (32.6%) had NERD.RE was significantly commoner in males and older individuals. The basal LES pressures and median IRP were significantly lower in the RE group(p<0.05). There was no significant difference in the EGJ morphology or peristalsitic abnormalities in the two groups<o:p></o:p></span></p> <p class="MsoNormal" style="margin-left:.25in;text-align:justify;text-justify: inter-ideograph;line-height:200%"><span lang="EN-IN" style="font-size:14.0pt; line-height:200%">Conclusion-Patients with RE are commonly males , older than NERD patients and have significantly lower LES pressure and median IRP.Majority of the cases have normal peristalsis. The commonest peristaltic abnormality noted is ineffective esophageal motility<o:p></o:p></span></p>
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Cite This Article:
Mayank Jain, Rajiv Baijal, Characteristics of lower esophageal sphincter function and esophageal motility noted on High Resolution Esophageal Manometry in patients with reflux disease, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : VOLUME-6 | ISSUE‾6 | JUNE-2017