Volume : 6, Issue : 7, July - 2017

ACASE REPORT OF MEDULLARY THYROID CARCINOMA: CYTOLOGICAL FEATURES AND THE ROLE OF PROCALCITONIN IN PREOPERATIVE DIAGNOSIS

Dr Sreechithra Kartha, Dr Ajith Rajan, Mr Umesh S. P

Abstract :

<p>&nbsp;<span style="font-family: &quot;Times New Roman&quot;, serif; font-size: 12pt;">Medullary thyroid carcinoma (MTC) is an unusual neuroendocrine thyroid neoplasm.Cytological diagnosis is difficult,as other thyroid neoplasms can mimicMTConfine needle aspiration cytology (FNAC).We present a case of MTCwhere the diagnosis was established by FNAC and semi-quantitativeprocalcitonin assay.FNAC showed a dispersed cell pattern,plasmacytoid morphology,cytoplasmic granules, and speckled chromatin. Calcitonin,the specific biomarker for MTC,has many drawbacks</span><span class="msoIns" style="font-family: &quot;Times New Roman&quot;, serif; font-size: 12pt;"><ins cite="mailto:Author" datetime="2017-05-01T21:30">,</ins></span><span style="font-family: &quot;Times New Roman&quot;, serif; font-size: 12pt;">which prompted us to measure serum procalcitonin.We are reporting this novel case because serum procalcitonin, a sepsis marker, is not routinely used as a marker for MTC.</span></p> <p class="MsoNormal" style="mso-margin-bottom-alt:auto;line-height:200%"><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Times New Roman&quot;,serif"><o:p></o:p></span></p>