Volume : 6, Issue : 6, June - 2017
Analysis of Modules in Protein-Protein Interaction Network of Clostridium tetani
Mohd Ayyubi, Tanvi, Kalpana, Ravins Dohare
Abstract :
<p> <span style="color: windowtext; font-family: "Times New Roman", serif; font-size: 12pt; text-align: justify;">Now-a-days, Graph-based approaches are widely used for the analysis of the different PPI networks such as for Clostridium tetani. As we know that most of the real network follows the scale free power law distribution. Thus the interactions among the proteins in the network follow heterogeneity with the other proteins in the bacteria due to the specific nature and characteristics of some of the proteins, whereas the random interactions among proteins follow homogeneity. This happens due to cohesively group of proteins are functioning for conclusive response of a particular function. Also, we have observed that the first module is involved mainly in biosynthetic process and is highly densed with comparatively high clustering coefficient among all the modules. These above findings may be useful for the researchers who are working in the area of proteomics and pharmaceutical research.</span></p> <p class="MsoNormalCxSpFirst" style="mso-margin-top-alt:auto;mso-margin-bottom-alt: auto;mso-add-space:auto;text-align:justify;line-height:200%"><span class="MsoSubtleEmphasis"><span style="font-size: 12pt; line-height: 200%; font-family: "Times New Roman", serif; color: windowtext;"><o:p></o:p></span></span></p>
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Download PDF Journal DOI : 10.15373/2249555XCite This Article:
Mohd Ayyubi, Tanvi, Kalpana, Ravins Dohare, Analysis of Modules in Protein-Protein Interaction Network of Clostridium tetani, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : VOLUME-6 | ISSUE‾6 | JUNE-2017