Volume : 8, Issue : 3, March - 2019

Clinical Presentation and Quality of Life in Patients with Acute Anterior Uveitis Associated with Seronegative Spondyloarthropathies

Gaile Gudauskiene, Lukas Semeklis, Dalia Zaliuniene, Goda Miniauskiene, Reda Zemaitiene

Abstract :

Aim of the study. To characterize clinical features and quality of life in patients with acute anterior uveitis (AAU) associated with seronegative spondyloarthropathies (SpA). Material and Methods. 68 SpA patients with or without AAU were included in the prospective clinical study. VF-14 questionnaire, macula OCT, lens opacities using LOCS III were assessed. Results. Macula was thicker in uveitic (279.31 (53.64) µm) compared to fellow eyes (261.52 (43.714) µm), p<0.05. More patients without AAU were treated with methotrexate, p<0.05. VF-14 values differed between LOCS III grade P1 (93.29 (11.21)) and P3 (80.36 (8.18)); C1 (92.79 (11.79)) and C2 (85.92 (17.17)) and C3 (74.05 (11.89)); NO1 (92.06 (14.17)) and NO3 (84.82 (9.22) scores), p<0.05. Conclusions. Maculae thickness in uveitic eyes was increased. More patients without AAU were treated with methotrexate. VF-14 scores were lower for patients with higher LOCS III grade and recurrent AAU.