Volume : 8, Issue : 3, March - 2019

MORPHOLOGICAL ANALYSIS OF EXFOLIATED BUCCAL AND TONGUE DORSUM CELLS IN TYPE II DIABETIC PATIENTS

Faseela Beegum P K, Shijineed T K, Sudha Sivasankar

Abstract :

Diabetes mellitus type 1 that results from immunologically mediated damage to the β-cells in the pancreas .Diabetes mellitus is characterized by recurrent or persistent hyperglycemia. Hyperglycemia can be associated with salivary gland dysfunction and alterations in the oral epithelial cells Aim: To study the morphologic changes of exfoliated epithelial cells from dorsal surface of tongue and buccal mucosa in Type II Diabetics. Methodology: We performed light microscopic analysis of the buccal and tongue dorsum smears in thirty type II diabetic patients and thirty healthy individuals. The oral smears were stained using Papanicolaou method for cytological examination. Morphological changes in the stained smears were identified by careful examination of the images captured under 40x magnification. Results: Diabetic patients showed an increased number of binucleated cells (p<0.01),intracytoplasmic inclusions(p<0.05),perinuclear halo(p<0.01).An increase in number of inflammatory cells (p<0.01) were also found in Type 2 Diabetic patients from dorsum of tongue. Conclusion: The light microscopic study indicates that type II diabetes can produce morphological changes in the oral mucosa that are noticeable with exfoliative cytology.