Volume : 8, Issue : 5, May - 2019

A comparative evaluation between three different doses of intrathecal 1% chloroprocaine for patients undergoing short duration lower limb surgery-A clinical study

Dr. Anshu Priyanka Lakra, Dr. Rajkumar Ahirwal, Dr. Urmila Keshari

Abstract :

Chloroprocaine is an amino ester local anesthetics with very short half life. Intrathecal 1% chloroprocaine represents an interesting alternative in patients undergoing short duration lower limb surgery when compared with spinal bupivacaine. This study evaluate the effect of 3 doses of chloroprocaine 1% 30,40 and 50mg for spinal anesthesia in adult patients undergoing short duration elective surgery of lower limb . Sixty ASA physical status I and II patients both male and female posted for various short duration lower limb surgeries under spinal anaesthesia were randomized into three group to receive one of the single doses of chloroprocaine 1% either 30mg,40mg or 50mg via intrathecal injection. The onset time of sensory and motor block, duration of sensory & motor block, maximum height of block, hemodynamic parameters was noted. Their hemodynamic parameters were stable and dermatomal level reached was T8-T10 in majority in the dose of 4ml&5ml of chlorprocaine . Serious side effect or neurological deficit associated with the drug did not occur in any patient in this study. We found 1% choloprocaine in the dose of 4ml and 5 ml to be effective spinal anaesthetic agent for short surgical procedure of lower limb.30 mg dose may not be suitable for lower limb procedure lasting ≤60 min. however correct patient and surgery selection allow a successful use also of the 30mg dose