Volume : 2, Issue : 11, November - 2013

Effects of Cadmium on the Olfactory Bulb of Albino Rat Fed with Zinc Deficient Diet

Dr S M Dawar Husain

Abstract :

Cadmium, an environmental pollutant, is reported to have toxic effects on nearly all systems of human body though it’s toxic effects nervous system are less well documented. It’s pathophysiological actions are related to body stores of Ca++, Zn++ and Na++. This investigation was conducted to explore the toxic effects of Cd++ on the olfactory bulb of albino rats fed with the Zn++ deficient diet, to have an idea about it’s corresponding toxic effects on humanbeings. 16 charles foster strain rats were taken. 8 rats (control group) and the remaining 8 rats (experimental group) were kept for 30 days on the stock ration and the Zn++ deficient diets, respectively. Experimental group rats were given Cd++ injections. Than 10µ thick sections of the olfactory bulb were stained with H&E, Thionine and Gleese silver stains. On microscopic observation, various layers of the olfactory bulb (of experimental group rats) showed degenerative changes