Volume : 2, Issue : 12, December - 2013

Comparative study of use of autologous bone grafts vs. artificial Beta TCP bone grafts in cases of spine fusion, lytic lesions, and other orthopaedic procedures

Dr Samir Patel, Dr Mukund M Prabhakar, Dr Himanshu Panchal, Dr Dipak A Shah

Abstract :

Aim– compare the results of Artificial bone graft substitutes to autologous grafts for of spine fusion, lytic lesions, other orthopaedic procedures at different sites and its rate of incorporation, in turn to ing out some useful results to potentially reduce or eliminate the need for autograft. Material and methods– A prospective study was conducted on patients with various indications by using bone graft substitutes at civil hospital, Ahmedabad during the period of June 2010 to December 2012.We have evaluated results of Autologous Bone grafts Vs Beta TCP bone grafts in various forms.Assessment of results with standard outcome measures was carried out through standard Proforma. Results– Spine Group: →Beta Tricalcium phosphate – patients got fusion at a period comparable to autogenous bone grafts. →Autologous Bone Grafts –Massive number of 95 patients undergone fusion done by Autologous bone grafts. All showed good results in union, and skin condition.Almost desired fusion occurred at about 2 months in all patients Lytic lesions and other procedures: →Beta Tricalcium phosphate –patients got lesion united at a period comparable to autogenous bone grafts.B– TCP proved good substitute for filling these lytic cavaties.Where massive bone grafting needed B–TCP provided good alternative ,when mixed with autologous bone marrow.→Autologous Bone Grafts –Cancellous Autlogous bone grafts proved to be excellent in cavity filling in lytic lesion.Almost desired fusion occurred at about 2.5 months in all patients. All showed good results in union, and skin condition. Conclusions– Autologous Bone Grafts are the age old gold standard method for any fusion procedures. Combination of autogenous cancellous bone grafts and bone graft substitutes are the next best available option. Bone graft substitutes alone can be helpful when only osteoconductivity property is needed for which careful patient selection is required.