Volume : 8, Issue : 11, November - 2019

Screening of pregnant women for presence of IgG antibodies for rubella, mumps, measles and varicella viruses in tertiary care hospital, Jaipur.

Dr. Seema Malav, Dr. Bharti Malhotra

Abstract :

Background : The aim of this study were assess the susceptible pregnant women for vaccine preventable infection like rubella, mumps, measles and varicella viruses. Infection of mothers with these viruses during pregnancy can be serious. They can cause congenital infections, miscarriage, stillbirth and death of fetuses. Material and Method : This study is cross sectional. To determine the presence of IgG antibodies for rubella, mumps, measles and varicella viruses, blood samples were collected, stored at -700 c. Serum was separated for detection of IgG antibodies for these viruses by using enzyme linked immunosorbant assay. Results : Of 277 samples evaluated for IgG antibodies. Susceptibility Of pregnant women for rubella, mumps measles and varicella viruses were 7.6%, 17.6%,7.2% and 19.5% respectively. Susceptibility rates for rubella and mumps were higher in rural population as compares to urban while for varicella urban population was more susceptible, but it was not statistically significant. No correlation could be observed in susceptibility to different to different viruses and their education status and age of patients, but youngest age group was most susceptible to varicella and oldest group to rubella. Primigravida were more susceptible to rubella and varicella while multigravida were more susceptible to mumps and measles. Conclusion : Majority of the pregnant women had protective levels of IgG antibody although susceptibility to rubella, mumps measles and varicella were low. Intensification of MMRV immunization of all females of child-bearing age is advocated.