Volume : 8, Issue : 11, November - 2019

A RARE CASE OF VALPROATE INDUCED HEPATO-TOXICITY

Dr. V. C. Singel, Dr. Kartikeya Parmar, Dr. Vijay Dhalavaniya, Dr. Khanjan Patel, Dr. Swansu Batra

Abstract :

Drug Induced Liver Injury(DILI) can occur owing to a dose dependent or idiosyncratic reaction to a drug. Valproate induced hepato-toxicity can lead to Acute hepatic failure, occasionally can progress to fulminant hepatic failure and may require liver transplantation. Valproate being a commonly used drug, most physicians need to exert a cautious approach for judicious use of the drug. Hereby, we aim to discuss different manifestations of Valproate induced Hepato-toxicity and it’s medical management.