Volume : 9, Issue : 4, April - 2020

COMPARISON BETWEEN TABLET METFORMIN AND INJECTION INSULIN IN THE TREATMENT OF GESTATIONAL DIABETES MELLITUS: PROSPECTIVE STUDY

Dr. Manjushri Waikar, Dr. Anju Jha

Abstract :

INTRODUCTION: Gestational diabetes mellitus is defined as glucose intolerance of different severity recognsied first time during pregnancy. GDM is diagnosed in 3-7% of pregnancies. The main purpose of treatment of GDM is to prevent hyperinsulinemia and fetal macrosomia by improving maternal glycemic control. AIM -To compare metformin and injection insulin in the treatment of GDM and its maternal and fetal outcome METHOD- In this prospective study conducted during (march 2018-september 2019) 100 Women include who visited in antenatal clinic and/or admitted in ward between 20-36 yr of age at gestational age between 20 to 36 weeks who were diagnosed by had done OGCT by DIPSI method and value more than >140 mg/dl diagnosed as GDM and 50 women were given Metformin and 50 were given Insulin. Results were compared. RESULTS: Both groups were comparable with respect to age, parity, family history of DM and weight gain during pregnancy. Glycemic control was slightly better in Insulin treated group than Metformin treated group throughout gestation (p value =0.38). CONCLUSION: . In this study we found that slightly better glycaemic control was found in Insulin group than Metformin group but there was no significant difference between two groups.