Volume : 9, Issue : 6, June - 2020

A COMPARITIVE STUDY

Dr. Diksha Babu Poojary, Dr. Akriti Gupta, Dr. J. Narshetty, Dr. Sushil Kumar, Dr. Rahul Khatri

Abstract :

Background: - Preterm delivery is a major reason behind perinatal morbidity and mortality. Numerous tocolytic agent are accustomed inhibit preterm labour among which calcium channel antagonist Nifedipine and beta mimetic Isoxsuprine is employed. The effectiveness of Nifedipine and Isoxsuprine is assessed during this prospective study. Materials and method: - A comparative, prospective and randomised distributed in 100patient within the department of obstetrics and gynaecology, MGM MEDICAL COLLEGE AND HOSPITAL, NAVI MUMBAI. The subjects were randomised into 2 group, first group receiving oral Nifedipine whereas second group receiving injectable Isoxsuprine followed by oral tablets. Results: - During this study, 50 women received oral nifedipine and 50 women received injectable isoxsuprine followed by oral tablets, successful tocolysis was achieved in 96% with Nifedipine group and 76% with isoxsuprine group. Conclusion: - Nifedipine as compared to isoxsuprine in management of preterm labour is significantly related to longer postponement of delivery with fewer maternal side effects.