Volume : 1, Issue : 4, September - 2012

Investigational Drugs in treatment of Alzheimer�s Disease: A Systematic Review

Dr. Deep Inder

Abstract :

Alzheimer’s disease (AD) is a chronic neurodegenerative disease affecting elderly between age 65–85 years and is characterized by progressive dementia sufficient to interfere with social and occupational functioning pathophysiologically there is loss of neurons, synaptic function and formation of amyloid plaques and neurofiillary tangles with profound deficit of Acetylcholine in ain. Presently, exiting treatments are acetylcholinesterase inhibitors and Mementine effective in mild AD. This review summarizes the upcoming investigational drugs in treatment of AD.