Volume : 3, Issue : 5, May - 2014

Mortality in HIV Exposed Infants and It's Determinants

Dr Dipti Agrwal, Dr Abnish Kumar, Dr Nirmal Chandra Prajapati, Dr. Saroj Singh

Abstract :

This prospective study was conducted to study mortality in HIV exposed infants and it’s determinants.30 infants born to HIV infected mothers receiving antiretroviral prophylaxis were included in the study group and 30 infants born to HIV non infected mothers (matched in gestational age) during the study period were taken as controls. 9 HIV exposed infants died in first 6 months (mean age 22 days ) as compared to one in control group. Amongst maternal factors associated with high infant mortality were advanced disease stage, low CD4 counts (p value =0.008, 0.03 respectively).Low Body mass index and anaemia (p value=0.004,0.06 respectively )also related significantly to high mortality . Low birth weight and prematurity (p value =0.01, 0.001 respectively) were the infant factors associated with high mortality. This early and high infant mortality despite prophylaxis warrants additional measures to reduce negative influence of HIV infection.