Volume : 4, Issue : 3, March - 2015

Evaluation of Histopathological Changes in Gallbladder Mucosa In Relation to Gallstones with duration.

Mohd. Arshad Raza, Jagadamba Sharan, Chandra Prakash Pandey, M. D. Tripathi

Abstract :

<p>&lt;p&gt;&amp;nbsp;Gallstone diseases are very common throughout the world including India. It is estimated that between 85% and 90%&amp;nbsp;&lt;/p&gt; &lt;div&gt;of patients who have gallstones remain asymptomatic and less than 20% chance to develop symptoms. There have&amp;nbsp;&lt;/div&gt; &lt;div&gt;risk of disease related complications such as acute cholecystitis, gallstone pancreatitis and choledocholithiasis. The&amp;nbsp;&lt;/div&gt; &lt;div&gt;present study was conducted on 100 patients of gallbladder diseases irrespective of gender aged between 11 to 65 years. Out of 100 patients&amp;nbsp;&lt;/div&gt; &lt;div&gt;cholecystectomy was carried out on 87 patients. 13 patients of gallbladder disease left the hospital before their full work&amp;ndash;up. The histopathological&amp;nbsp;&lt;/div&gt; &lt;div&gt;evaluation revealed that 44 cases (50.57%) were having only chronic cholecystitis with cholelithiasis, 18 cases (20.69%) were of acute on chronic&amp;nbsp;&lt;/div&gt; &lt;div&gt;cholecystitis with cholelithiasis, 13 cases (14.94%) were of Chronic cholecystitis with cholelithiasis with Metaplasia of gallbladder mucosa, 9 cases&amp;nbsp;&lt;/div&gt; &lt;div&gt;(10.34%) were of Chronic cholecystitis with cholelithiasis with Dysplasia of gallbladder mucosa,3 cases (3.45%) were of Chronic cholecystitis with&amp;nbsp;&lt;/div&gt; &lt;div&gt;cholelithiasis with Carcinoma gallbladder (Adenocarcinoma). Prophylactic cholecystectomy can be offered to patients having asymptomatic&amp;nbsp;&lt;/div&gt; &lt;div&gt;cholelithiasis as there is high incidence of gallstone related complications including carcinoma gallbladder.&lt;/div&gt;</p>