Volume : 4, Issue : 7, July - 2015

Wound Healing Activity Of Ethanolic Extract Of Chromolaena Odorata L. On Excision Wound Model In Rats

R. Shiney Monica, Dr. K. Revathi

Abstract :

<p>Chromolaena odorata (L. f.) King and Robinson formerly called as Eupatorium odoratum belongs to the family Asteraceae. C.odorata is a perennial scandent or semi-woody shrub. The aqueous extract and the decoction from leaves of this plant have been used throughout Vietnam for the treatment of soft tissue wounds and burns. The present study was aimed at evaluation of wound healing activity of leaves of C.odorata. Healthy male Wistar albino rats were topically treated with extract formulated in gel (10% and 20% of C.odorata ). Rats of standard groups were treated with 5% w/w povidone-Iodine ointment topically. The percentage of wound contraction was measured. Topical application of C.odorata gel in excision wound model increased percentage of wound contraction. The experimental data revealed that the C. odorata displayed remarkable wound healing and thus supports its traditional use.</p>