Volume : 4, Issue : 11, November - 2015

Drug Resistant Tuberculosis in Children- Risk Factors and Therapeutic Response

Dipti Agarwal, Shamrendra Narayan, Manoj Kumar, Santosh Kumar

Abstract :

<p>33 children less than 18 years of age (mean age 15.6 years) were resistant to both isoniazid and rifampicin from 2010 January to March 2015 .Of these, 6 died within 2 months, 25 patients were on treatment with category 4 antitubercular drugs for mean duration of 12.72 months. Contact (mostly household) with drug resistant tuberculosis (DRTB) cases was found in 9 (36%) subjects . Treatment outcome in these 25 (75.6%) subjects showed clinical and microbiological improvement. To conclude, contact with DR TB case is important risk factor for DR TB in children. Moreover, good treatment outcomes of cases can be obtained in DR TB cases in children if timely initiated.</p>