Volume : 5, Issue : 1, January - 2016

LONG PENTRAXIN PTX3 AND ITS CORRELATION WITH SEVERITY OF PSORIASIS

Dr. Bandana Kumari

Abstract :

<p>Psoriasis is a chronic, autoimmune, inflammatory cutaneous disease with systemic involvement. Main aim of this study was to evaluate long Pentraxin PTX3 as a marker for disease activity in Psoriasis patients and to establish its relationship with disease severity. Plasma Pentraxin PTX3 was analyzed in 50 Psoriasis patients of 20-50 years age group .50 age and sex matched healthy volunteers were taken as control. Result showed that Plasma levels of long Pentraxin PTX3 were significantly higher in Psoriasis patients compared to controls with p value &lt; 0.0001. Also PTX3 level correlated significantly with disease severity in Psoriasis patients (grouped as mild, moderate and severe according to PASI score).So Long Pentraxin PTX3 may be regarded as a reliable biomarker of disease activity in Psoriasis patients and also to access disease severity in these patients.</p>