Volume : 5, Issue : 11, November - 2016

A COMPARISON BETWEEN DEXMEDETOMIDINE AND ESMOLOL FOR INDUCED HYPOTENSION IN FUNCTIONAL ENDOSCOPIC SINUS SURGERIES

Vasukinathan Arokyamuthu, Pratheeba Durairaj, Edward Johnson Joseph, J. Rosebell

Abstract :

<p>&nbsp;Background and goals of study: Induced Hypotension is a method used to reduce bleeding and thereby improve the quality of surgical field during FESS. This study compares the efficacy and safety of Dexmedetomidine and Esmolol as hypotensive agents in Functional Endoscopic Sinus Surgeries. Methods: We included 60 ASA l &amp;ll patients in the study. Patients were randomly allocated to two groups. Group A (n= 30) : Patients receiving Dexmedetomidine. Group B (n= 30) : Patients receiving Esmolol. In Group A, patients received loading dose of 1 &mu;g/kg Dexmedetomidine diluted in 10 ml 0.9% saline infused over 10 min, before induction of anesthesia, followed by continuous infusion of 0.4 &ndash; 0.8 &mu;g/kg/h. In Group B, patients received Esmolol as a loading dose 1 mg/kg, infused over 1 min, before induction of anesthesia, followed by continuous infusion of 0.4-0.8 mg/kg/h. The surgical field was assessed using Average Category Scale. Intraoperative hemodynamic parameters were recorded. Results: Both Dexmedetomidine and Esmolol were effective in maintaining the intraoperative mean arterial pressure within the target range. Heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure were comparable between the two groups during the intraoperative period till the stoppage of the study drug. Average Category Scale was comparable between the two groups. Conclusion: Both Dexmedetomidine and Esmolol are effective in providing ideal surgical conditions during Functional Endoscopic Sinus Surger</p>