Volume : 6, Issue : 1, January - 2017

A COMPARATIVE STUDY TO ASSESS THE BEHAVIORAL CHANGES BETWEEN THE SLEEP DEPRIVATION AND NOISE STRESS INDUCED MICE

Suresh K, Suganya K, Kayalvizhi E, Chandrasekar M.

Abstract :

<p>&nbsp;Humans are exposed to a number of stressors in the daily routine life and among them noise and sleep deprivation is the most encountered stressor. This two stressor an associated with disorders like anxiety and depression which are functional major disorders we see daily. The aim of this study was to compare the behavioral changes between sleep deprived and noise stress induced mice. 18 swiss albino mice weighing 20-25gms were taken in this study and they were divided into three groups with six mice in each group (Group I- control, Group II- noise stressed mice and Group III - Sleep deprived mice). Immediately after sleep deprivation for about 96 hrs for four consecutive days and noise stress with 200 Hz&rsquo;s 120 db, 30 min/day for 12 consecutive days, the mice were exposed to behavioral analysis. In our study, there was a significant decrease in behavior parameters in both noise stressed and sleep deprived mice, but it was highly significant in the sleep deprivation group. Our findings reveals that sleep deprivation reduces locomotor activity with altered behaviors suggest that sleep deprivation is potent stressor than noise stress.</p>