Volume : 6, Issue : 1, January - 2017

Pathology of Dengue Fever- Autopsy Study in a Tertiary Care Hospital.

Dr. Rakesh Shedge, Dr. Vikas Kavishwar, Dr. Varsha Dhume, Dr. Lalita Patil

Abstract :

<p>&nbsp;Objective : To study gross and microscopic pathology in various organs in serologically proven dengue related deaths. Materials &amp;Methods : Autopsies carried out in fatal dengue cases from January 2015 to December 2016 were analysed. Results : Complete autopsies were conducted in all 8 cases of dengue fatalities. Edema and intrapulmonary hemorrhage were significant pathologies in lungs. Acute tubular necrosis of kidney was noted in majority of cases. Hemorrhage in the gastrointestinal mucosa, hepatic necrosis and myocardial interstitial haemorrhage were occasionally observed. Conclusion :Dengue fever should be regarded as a multiorgan infection. Autopsy studies will enlighten pathology in different organs. A better understanding of changes in different organs in dengue fever will help in the management and prevent fatalities.</p>