Volume : 6, Issue : 5, May - 2017

Study of osteoporosis in postmenopausal woman and its relation to vitamin D deficiency and daily calcium intake.

Dr. Prajakta Sawai Aswar

Abstract :

<p>&nbsp;<b style="text-align: justify;"><span style="font-family:&quot;Arial&quot;,sans-serif">Objective:</span></b></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph;&#10;line-height:200%"><span style="font-family:&quot;Arial&quot;,sans-serif;mso-bidi-font-weight:&#10;bold">We evaluated the combined effects of vitamin D and daily calcium intake on bone mineral density (BMD) and osteoporosis in the postmenopausal women.<o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph;&#10;line-height:200%"><b><span style="font-family:&quot;Arial&quot;,sans-serif">Methods<o:p></o:p></span></b></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph;&#10;line-height:200%"><span style="font-family:&quot;Arial&quot;,sans-serif;mso-bidi-font-weight:&#10;bold">This study is a cross-sectional record based study consisting of 1,921 postmenopausal women aged 45 to 70 years without thyroid dysfunction, from 2006 to 2012. <o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph;&#10;line-height:200%"><b><span style="font-family:&quot;Arial&quot;,sans-serif">Results:<o:p></o:p></span></b></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph;&#10;line-height:200%"><span style="font-family:&quot;Arial&quot;,sans-serif;mso-bidi-font-weight:&#10;bold">The BMD divided according to serum 25(OH)D and daily calcium intakes were not statistically different among the groups. However, when both daily calcium intake and serum 25(OH)D were not sufficient, risk of osteopenia and osteoporosis showed significant increase in both femur neck and lumbar spine (odds ratio [OR] 2.242,&nbsp;<i>P</i>=0.006; OR 3.044,&nbsp;<i>P</i>=0.001; respectively). <o:p></o:p></span></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph;&#10;line-height:200%"><b><span style="font-family:&quot;Arial&quot;,sans-serif">Conclusion<o:p></o:p></span></b></p> <p class="MsoNormal" style="text-align:justify;text-justify:inter-ideograph;&#10;line-height:200%"><span style="font-family:&quot;Arial&quot;,sans-serif;mso-bidi-font-weight:&#10;bold">The combined effects of insufficient daily calcium intake and vitamin D deficiency may cause low BMD and increase in prevalence of osteopenia and osteoporosis in the postmenopausal women aged 45 to 70 years.<o:p></o:p></span></p>