Volume : 6, Issue : 7, July - 2017

ANTIBIOTIC SUSCEPTIBILITY PATTERN OF BACTERIAL ISOLATES IN WOUND INFECTION IN A TERTIARY CARE HOSPITAL

Pavani G.

Abstract :

<p>&nbsp;<b style="text-align: justify;"><span style="font-size:12.0pt;font-family:&#10;&quot;Times New Roman&quot;,serif">Objectives:</span></b><span style="text-align: justify; font-size: 12pt; font-family: &quot;Times New Roman&quot;, serif;"> To determine the causative aerobic bacteria causing wound infection and to determine their antimicrobial sensitivity pattern.</span></p> <p class="Default"><b>Material and methods: </b>Pus&nbsp;&nbsp; samples were collected from patients&nbsp;&nbsp; with wound infections and &nbsp;subjected to gram staining and aerobic bacterial culture . The isolates were identified by standard identification procedures .Antimicrobial susceptibility testing of the isolates was done by Kirby Bauer disc diffusion method. <b>Results : A total of </b>112 samples were processed over a period of 6 months. The most common isolate was Stapylococcus aureus followed&nbsp; by Klebsiella . Vancomycin(100%) followed by&nbsp; Amikacin(88.6%) were the most effective antimicrobial agents effective against S. aureus. The gramnegative isolates showed maximum sensitivity to&nbsp; amikacin&nbsp; (80-100%) and gentamicin (40-100%) .<b> Conclusion :</b> <span style="color:#221E1F">Vancomycin and</span> Amikacin<span style="color:#221E1F">&nbsp; are the most effective drugs in wound infection due to grampositive &nbsp;and </span>&nbsp;&nbsp;&nbsp;Gram- negative bacteria respectively<span style="color:#221E1F"> . </span>Penicillins, macrolides and third generation cephalosporins should not be used as empiric therapy of wound infection&nbsp;<o:p></o:p></p>