Volume : 6, Issue : 8, August - 2017

A Comparative study of Sublingual Misoprostol 400 �g with Intramuscular Carboprost 125 �g in Active Management of Third stage of Labour

S Karpagam, P Bakiavathy

Abstract :

<p>&nbsp;<b><span style="font-size:12.0pt;&#10;line-height:200%;mso-bidi-font-family:Calii;mso-bidi-theme-font:minor-latin">Objectives:</span></b><span style="font-size: 12pt; line-height: 200%;">&nbsp;To </span><span style="background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial; font-size: 12pt; line-height: 200%;">compare sublingual misoprostol 400 &micro;g with Intramuscular carboprost 125 &micro;g in active management of third stage of labour. </span><b><span style="font-size:12.0pt;line-height:200%;mso-bidi-font-family:&#10;Calii;mso-bidi-theme-font:minor-latin">Materials and methods:</span></b><span style="font-size: 12pt; line-height: 200%;"> <span style="background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;">300 full term pregnant women delivering vaginally were randomly divided in two groups. The first group received 400 &micro;g sublingual misoprostol and the second group received intramuscular carboprost 125 &micro;g immediately after delivery. </span></span><b><span style="font-size:12.0pt;line-height:200%;&#10;mso-bidi-font-family:Calii;mso-bidi-theme-font:minor-latin">Results</span></b><span style="font-size: 12pt; line-height: 200%;">: </span><span style="background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial; font-size: 12pt; line-height: 200%;">The mean duration of labour and blood loss in sublingual <a name="_Hlk487394317">misoprostol group (3.05&plusmn;0.80 hrs,125.50&plusmn;21.80ml) </a>was less compared to the Intramuscular carboprost group (4.20&plusmn;1.20 hrs,194.70&plusmn;30.40ml) and it was</span><span style="font-size: 12pt; line-height: 200%;"> statistically significant (</span><i><span style="font-size: 12pt; line-height: 200%;">P</span></i><span style="font-size: 12pt; line-height: 200%;">&nbsp;&lt; 0.0001)</span><span style="background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial; font-size: 12pt; line-height: 200%;">. </span><b><span style="font-size:12.0pt;line-height:200%;mso-bidi-font-family:Calii;&#10;mso-bidi-theme-font:minor-latin">conclusion</span></b><span style="font-size: 12pt; line-height: 200%;">:</span><span style="background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial; font-size: 12pt; line-height: 200%;"> sublingual misoprostol is better than Intramuscular carboprost for active management of third stage of labour.</span></p> <p class="MsoNormal" style="line-height:200%"><span style="font-size: 12pt; line-height: 200%; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;"><o:p></o:p></span></p>