Volume : 6, Issue : 9, September - 2017

PRE AND POST-OPERATIVE NEUTROPHIL RESPONSE IN THE ELDERLY

Dr. Shweta, Dr. A. Santa Kumari, Dr. Aruna

Abstract :

<p>&nbsp;<span style="font-family: &quot;Times New Roman&quot;, serif; font-size: 16pt;">Ageing is associated with a decline in many of the human body&rsquo;s functions, including that of the immune system. The negative impact of ageing on immunity is called </span><b style="font-family: &quot;Times New Roman&quot;, serif; font-size: 16pt;">IMMUNOSENESCENCE</b><span style="font-family: &quot;Times New Roman&quot;, serif; font-size: 16pt;">; where the function of various components of both the innate and acquired immune system is attenuated with important consequences to health and disease. </span><span style="font-family: &quot;Times New Roman&quot;, serif; font-size: 16pt;">Interestingly, it would appear that the number of neutrophils in circulation is not affected by age, although there is evidence of decreased </span><b style="font-family: &quot;Times New Roman&quot;, serif; font-size: 16pt;">PHAGOCYTOSIS</b><span style="font-family: &quot;Times New Roman&quot;, serif; font-size: 16pt;"> and reduced superoxide production. In addition, surgical stress is forbidding HOMEOSTASIS. The goal is to identify the variance in neutrophil count &amp; phagocytosis, as neutrophils</span><span style="font-family: &quot;Times New Roman&quot;, serif; font-size: 16pt;">&nbsp; </span><span style="font-family: &quot;Times New Roman&quot;, serif; font-size: 16pt;">are the 1</span><sup style="font-family: &quot;Times New Roman&quot;, serif;">ST</sup><span style="font-family: &quot;Times New Roman&quot;, serif; font-size: 16pt;"> LINE OF DEFENCE FOR HOST IMMUNITY</span></p> <p class="MsoNormal" style="margin-top:0in;margin-right:-36.6pt;margin-bottom:&#10;10.0pt;margin-left:-28.35pt;line-height:normal"><span lang="EN-IN" style="font-size:16.0pt;font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><o:p></o:p></span></p>