Volume : 6, Issue : 9, September - 2017

A STUDY OF SYMPTOM DIMENSIONS AND THEIR EFFECT ON TREATMENT RESPONSE IN PATIENTS WITH OBSESSIVE COMPULSIVE DISORDER

Dr. D. Asha Mounika, Dr. Omesh Kumar

Abstract :

<p>&nbsp;<b><u><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;&#10;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">Aims And Objectives</span></u></b><b><span lang="EN-IN" style="font-size:12.0pt;&#10;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">:</span></b><span lang="EN-IN" style="font-size: 12pt; line-height: 200%; font-family: Arial, sans-serif;"> </span><span style="font-size: 12pt; line-height: 200%; font-family: Arial, sans-serif;">To study symptom dimensions in OCD and their effect on treatment response in OCD patients.</span></p> <p class="MsoListParagraph" style="margin-left:0in;mso-add-space:auto;line-height:&#10;200%"><b><u><span style="font-size:12.0pt;&#10;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">Methods and&nbsp; materials</span></u></b><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">: Patients&nbsp; diagnosed&nbsp; OCD( ICD-10)&nbsp; at&nbsp; OP&nbsp; setting were included in the study and were&nbsp; followed&nbsp; up&nbsp; for&nbsp; three&nbsp; months&nbsp; under&nbsp; treatment&nbsp; with&nbsp; SSRIs. YBOCS symptom checklist</span><span style="font-size:12.0pt;&#10;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-ansi-language:EN-IN"> </span><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">and severity scale are administered at the point of entry into study. </span><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;&#10;mso-ansi-language:EN-IN">After 12 wks of treatment</span><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">, YBOCS severity scale is </span><span lang="EN-IN" style="font-size:12.0pt;&#10;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;mso-ansi-language:EN-IN">re-</span><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">administered. <o:p></o:p></span></p> <p class="MsoNormal" style="line-height:200%"><b><u><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;&#10;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">Results</span></u></b><b><i><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">:</span></i></b><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;&#10;mso-ansi-language:EN-US"> Of&nbsp; 49&nbsp; patients most(40) had both obsessions and compulsions. The most common obsession was contamination(30.6%) and compulsion was washing/cleaning(34.6%) . Subtype of obsessions (p = 0.041) and presence of multiple obsessions( p = 0.03) were found to be significantly different between responders and non responders. <o:p></o:p></span></p> <p class="MsoNormal" style="line-height:200%"><b><u><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;&#10;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">Conclusion</span></u></b><b><i><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">: </span></i></b><span lang="EN-IN" style="font-size:12.0pt;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;&#10;mso-ansi-language:EN-US">&nbsp;</span><span style="font-size:12.0pt;line-height:200%;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;&#10;mso-ansi-language:EN-US">Few subtypes of obsessions( sexual/religious)&nbsp; and presence of multiple obsessions were&nbsp; found&nbsp; to&nbsp; be&nbsp; associated with poor treatment &nbsp;response in patients with OCD.<o:p></o:p></span></p>