Volume : 6, Issue : 11, November - 2017

HYPOCALCEMIA AS A PROGNOSTIC MARKER FOR SEVERITY IN PATIENTS WITH DENGUE FEVER

Dr Thanuj Reddy, Dr Vishwanath Reddy, Dr Lakshmaiah V, Dr Rakesh Garlapati

Abstract :

<p>&nbsp;<b><span lang="EN-IN" style="font-size:14.0pt">INTRODUCTION</span></b><span lang="EN-IN" style="font-size: 14pt;">: Dengue fever is a major cause of morbidity and mortality. Serum free calcium (Ca2+) plays an important role in cardiac and circulatory function.</span></p> <p class="Default"><b><span lang="EN-IN" style="font-size:14.0pt">METHODOLOGY</span></b><span lang="EN-IN" style="font-size:14.0pt">: This cross-sectional study was done at RLJ hospital in Kolar, Karnataka. All probable cases of dengue were diagnosed and classified according to World Health Organization criteria. <a name="_Hlk497943493"><o:p></o:p></a></span></p> <p class="Default"><b><span lang="EN-IN" style="font-size:14.0pt">RESULTS</span></b><span lang="EN-IN" style="font-size:14.0pt">: The mean age was 40.8 years, and the majority were males (n = 79, 52.6%). Mean serum Ca2+ was significantly lower in patients with severe dengue (4.16mg/dl) than in those with dengue fever without warning signs and with warning signs (4.66mg/dl,4.36mg/dl) (p &lt; 0.001). <o:p></o:p></span></p> <p class="Default"><b><span lang="EN-IN" style="font-size:14.0pt">CONCLUSIONS</span></b><span lang="EN-IN" style="font-size:14.0pt">: Serum Ca2+ levels significantly correlated with dengue severity. Hypocalcaemia is significantly prevalent in patients with severe form than in patients of Dengue with and without warning signs.&nbsp;<o:p></o:p></span></p>