Volume : 6, Issue : 12, December - 2017

STUDY OF TUBERCULOSIS AND CRYPTOCOCCAL MENINGITIS IN HIV INFECTED PATIENTS AND THEIR CORRELATION WITH CD4 COUNT

Dr. Rita Singh Saxena, Dr. Anita Arya

Abstract :

Aim To study clinical and CSF profile of Tubercular and Cryptococcal meningitis in HIV infected hospitalised patients and to correlate clinical profile with CD-4 count. Methodology All the admitted HIV positive patients whose clinical manifestations were suggestive of meningitis, were screened by CSF analysis and specific diagnosis made according to CSF findings. CSF-AFB stain, CSF cultur , and india ink preparation were also done to make the diagnosis more accurate. CD-4 count of every HIV sereopositive meningitis patients was determined using flow-cytometry<o:p></o:p> Results In our study, thirty seven meningitis patients were HIV positive. Patient’s age ranges from 20-70 years. We found only two types of meningitis in our study- Tubercular meningitis and Cyptococcal meningitis. 81.08% of patients had Tubercular meningitis and 18.91% of patients had Cyptococcal meningitis in our study. Tubercular meningitis was significantly more common than Cryptococcal meningitis.<o:p></o:p> Conclusion HIV infected patients are at high risk for opportunistic infections including meningeal involvement. Severe manifestations of meningitis keeps on increasing with decrease in CD-4 count. By early diagnosis and management of HIV positive patients with HAART- Highly Active Anti Retroviral Therapy we can keep CD-4 count of patient elevated to prevalent TB meningitis and Cryptococcal meningitis and also the sequel of disease.<o:p></o:p>

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Download PDF Journal DOI : 10.15373/2249555X

Cite This Article:

Dr. Rita Singh Saxena, Dr. Anita Arya, STUDY OF TUBERCULOSIS AND CRYPTOCOCCAL MENINGITIS IN HIV INFECTED PATIENTS AND THEIR CORRELATION WITH CD4 COUNT, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : VOLUME-6, ISSUE-12, DECEMBER-2017